Definition: EPO: = erythropoietin A glycoprotein hormon-like structure, a sialoglycoprotein, which is an important factor in the survival, growth and proliferation of erythroid precursor cells (EPC) and it improves the de novo creation, differentation and growth of red blood cells (RBC). Thus, EPO controls the erythropoiesis = production of RBC. EPC: these are cells that are located in the bone marrow, will eventually form the RBC. RBC: cells responsible for the transport and distribution of oxygen throughout the body. Structure: Built out of 165 aminoacids (AA). They are all connected and form 1 polypeptide chain. Although, within the chain, there are 2 disulfide bonds. Respectively on positions: Cys7-161 and Cys29-33 Cys = cystein and the numbers indicate the positions these AA are located. Cystein structure. Available sulfide group for bonding There are also 4 positions where there is a possibility for glycosylation Namel...
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